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Combining empirical knowledge, in silico molecular docking and ADMET profiling to identify therapeutic phytochemicals from Brucea antidysentrica for acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the deadly cancers. Chemotherapy is the first-line treatment and the only curative intervention is stem cell transplantation which are intolerable for aged and comorbid patients. Therefore, finding complementary treatment is still an active research area. For t...

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Detalles Bibliográficos
Autores principales: Bultum, Lemessa Etana, Tolossa, Gemechu Bekele, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328557/
https://www.ncbi.nlm.nih.gov/pubmed/35895695
http://dx.doi.org/10.1371/journal.pone.0270050