Increased concentrations of bioactive adrenomedullin subsequently to angiotensin‐receptor/neprilysin‐inhibitor treatment in chronic systolic heart failure

AIMS: The clinically investigated rationale for neprilysin (NEP)‐inhibition by angiotensinreceptor‐NEPinhibitor (ARNi) therapy is to induce elevations in endogenous natriuretic peptides. NEP, however, cleaves a broad spectrum of substrates, which partially hold significant implications in heart fail...

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Detalles Bibliográficos
Autores principales: Arfsten, Henrike, Goliasch, Georg, Bartko, Philipp E., Prausmüller, Suriya, Spinka, Georg, Cho, Anna, Novak, Johannes, Haslacher, Helmuth, Strunk, Guido, Struck, Joachim, Hülsmann, Martin, Pavo, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328655/
https://www.ncbi.nlm.nih.gov/pubmed/32598074
http://dx.doi.org/10.1111/bcp.14442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328655/
https://www.ncbi.nlm.nih.gov/pubmed/32598074
http://dx.doi.org/10.1111/bcp.14442

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