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Increased concentrations of bioactive adrenomedullin subsequently to angiotensin‐receptor/neprilysin‐inhibitor treatment in chronic systolic heart failure
AIMS: The clinically investigated rationale for neprilysin (NEP)‐inhibition by angiotensinreceptor‐NEPinhibitor (ARNi) therapy is to induce elevations in endogenous natriuretic peptides. NEP, however, cleaves a broad spectrum of substrates, which partially hold significant implications in heart fail...
Autores principales: | Arfsten, Henrike, Goliasch, Georg, Bartko, Philipp E., Prausmüller, Suriya, Spinka, Georg, Cho, Anna, Novak, Johannes, Haslacher, Helmuth, Strunk, Guido, Struck, Joachim, Hülsmann, Martin, Pavo, Noemi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328655/ https://www.ncbi.nlm.nih.gov/pubmed/32598074 http://dx.doi.org/10.1111/bcp.14442 |
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