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M351‐0056 is a novel low MW compound modulating the actions of the immune‐checkpoint protein VISTA

BACKGROUND AND PURPOSE: The protein V‐domain immunoglobulin suppressor of T‐cell activation (VISTA) is a novel immune‐checkpoint molecule that belongs to the B7 family and regulates a broad spectrum of immune responses. So far, low MW compounds targeting VISTA for the treatment of autoimmune disease...

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Detalles Bibliográficos
Autores principales: Hu, Xinlei, Qie, Chenxin, Jiang, Jingwei, Xie, Xiaoxue, Chen, Wenting, Liu, Wanmei, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328666/
https://www.ncbi.nlm.nih.gov/pubmed/33450048
http://dx.doi.org/10.1111/bph.15357