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Synaptic pathology in Huntington’s disease: Beyond the corticostriatal pathway

Huntington’s disease (HD) is a heritable, fatal neurodegenerative disorder caused by a mutation in the Huntingtin gene. It is characterized by chorea, as well as cognitive and psychiatric symptoms. Histopathologically, there is a massive loss of striatal projection neurons and less but significant l...

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Detalles Bibliográficos
Autores principales: Barry, Joshua, Bui, Minh T.N., Levine, Michael S., Cepeda, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328779/
https://www.ncbi.nlm.nih.gov/pubmed/34848336
http://dx.doi.org/10.1016/j.nbd.2021.105574