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Synaptic pathology in Huntington’s disease: Beyond the corticostriatal pathway
Huntington’s disease (HD) is a heritable, fatal neurodegenerative disorder caused by a mutation in the Huntingtin gene. It is characterized by chorea, as well as cognitive and psychiatric symptoms. Histopathologically, there is a massive loss of striatal projection neurons and less but significant l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328779/ https://www.ncbi.nlm.nih.gov/pubmed/34848336 http://dx.doi.org/10.1016/j.nbd.2021.105574 |