Dehydroepiandrosterone (DHEA) Sensitizes Irinotecan to Suppress Head and Neck Cancer Stem-Like Cells by Downregulation of WNT Signaling

PURPOSE: Current treatment options for head and neck squamous cell carcinoma (HNSCC) are limited, especially for cases with cancer stem cell-induced chemoresistance and recurrence. The WNT signaling pathway contributes to maintenance of stemness via translocation of β-catenin into the nucleus, and r...

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Detalles Bibliográficos
Autores principales: Li, Li-Jie, Li, Chien-Hsiu, Chang, Peter Mu-Hsin, Lai, Tsung-Ching, Yong, Chen-Yin, Feng, Sheng-Wei, Hsiao, Michael, Chang, Wei-Min, Huang, Chi-Ying F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328800/
https://www.ncbi.nlm.nih.gov/pubmed/35912234
http://dx.doi.org/10.3389/fonc.2022.775541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328800/
https://www.ncbi.nlm.nih.gov/pubmed/35912234
http://dx.doi.org/10.3389/fonc.2022.775541

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