Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides

There are 660 pyrrolizidine alkaloids (PAs) and PA N-oxides present in the plants, with approximately half being possible carcinogens. We previously reported that a set of four PA-derived DNA adducts is formed in the liver of rats administered a series of hepatocarcinogenic PAs and a PA N-oxide. Bas...

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Detalles Bibliográficos
Autores principales: He, Xiaobo, Xia, Qingsu, Woodling, Kellie, Lin, Ge, Fu, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328871/
https://www.ncbi.nlm.nih.gov/pubmed/28987376
http://dx.doi.org/10.1016/j.jfda.2017.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328871/
https://www.ncbi.nlm.nih.gov/pubmed/28987376
http://dx.doi.org/10.1016/j.jfda.2017.09.001

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