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Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides
There are 660 pyrrolizidine alkaloids (PAs) and PA N-oxides present in the plants, with approximately half being possible carcinogens. We previously reported that a set of four PA-derived DNA adducts is formed in the liver of rats administered a series of hepatocarcinogenic PAs and a PA N-oxide. Bas...
Autores principales: | He, Xiaobo, Xia, Qingsu, Woodling, Kellie, Lin, Ge, Fu, Peter P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taiwan Food and Drug Administration
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328871/ https://www.ncbi.nlm.nih.gov/pubmed/28987376 http://dx.doi.org/10.1016/j.jfda.2017.09.001 |
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