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TRUST4: immune repertoire reconstruction from bulk and single-cell RNA-seq data

We introduce the TRUST4 open-source algorithm for reconstructing immune receptor repertoires in αβ/γδ T-cells and B-cells from RNA-seq data. Compared to competing methods, TRUST4 supports both FASTQ and BAM formats, is faster and more sensitive in assembling longer, even full-length, receptor repert...

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Detalles Bibliográficos
Autores principales: Song, Li, Cohen, David, Ouyang, Zhangyi, Cao, Yang, Hu, Xihao, Liu, X. Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328942/
https://www.ncbi.nlm.nih.gov/pubmed/33986545
http://dx.doi.org/10.1038/s41592-021-01142-2