miR-135a-5p Suppresses TBK1 and Activates NRF2/TXNIP Antioxidant Pathway in LPS-Driven ALI in Mice

OBJECTIVE: Acute inflammation and oxidative stress are present in large numbers in patients with acute lung injury (ALI). This investigation probed miR-135a-5p/TBK1 axis within ALI together with its new therapeutic target. METHODS: MLE-12 cultures were treated with lipopolysaccharide (LPS) and trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Guotao, Zeng, Yiwen, Wang, Yingjuan, Luo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329002/
https://www.ncbi.nlm.nih.gov/pubmed/35912153
http://dx.doi.org/10.1155/2022/9088727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329002/
https://www.ncbi.nlm.nih.gov/pubmed/35912153
http://dx.doi.org/10.1155/2022/9088727

Ejemplares similares