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miR-135a-5p Suppresses TBK1 and Activates NRF2/TXNIP Antioxidant Pathway in LPS-Driven ALI in Mice
OBJECTIVE: Acute inflammation and oxidative stress are present in large numbers in patients with acute lung injury (ALI). This investigation probed miR-135a-5p/TBK1 axis within ALI together with its new therapeutic target. METHODS: MLE-12 cultures were treated with lipopolysaccharide (LPS) and trans...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329002/ https://www.ncbi.nlm.nih.gov/pubmed/35912153 http://dx.doi.org/10.1155/2022/9088727 |