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DL-3-N-Butylphthalide Promotes Cartilage Extracellular Matrix Synthesis and Inhibits Osteoarthritis Development by Regulating FoxO3a

Osteoarthritis (OA) has been reported as a progressive disease in the elderly, primarily characterized by degenerated articular cartilage. There has been no satisfactory drug for the treatment of OA. DL-3-n-butylphthalide (NBP), a small molecule compound extracted from celery seeds, may have antiapo...

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Detalles Bibliográficos
Autores principales: Zhang, Yaxin, Dai, Jihang, Yan, Lianqi, Lin, Qun, Miao, Haixiang, Wang, Xingkai, Wang, Jingcheng, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329036/
https://www.ncbi.nlm.nih.gov/pubmed/35910845
http://dx.doi.org/10.1155/2022/9468040