Cargando…

Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I

Oocytes form before birth and remain viable for several decades before fertilization(1). Although poor oocyte quality accounts for most female fertility problems, little is known about how oocytes maintain cellular fitness, or why their quality eventually declines with age(2). Reactive oxygen specie...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Nuevo, Aida, Torres-Sanchez, Ariadna, Duran, Juan M., De Guirior, Cristian, Martínez-Zamora, Maria Angeles, Böke, Elvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329100/
https://www.ncbi.nlm.nih.gov/pubmed/35859172
http://dx.doi.org/10.1038/s41586-022-04979-5