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Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I
Oocytes form before birth and remain viable for several decades before fertilization(1). Although poor oocyte quality accounts for most female fertility problems, little is known about how oocytes maintain cellular fitness, or why their quality eventually declines with age(2). Reactive oxygen specie...
Autores principales: | Rodríguez-Nuevo, Aida, Torres-Sanchez, Ariadna, Duran, Juan M., De Guirior, Cristian, Martínez-Zamora, Maria Angeles, Böke, Elvan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329100/ https://www.ncbi.nlm.nih.gov/pubmed/35859172 http://dx.doi.org/10.1038/s41586-022-04979-5 |
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