Mechanisms of APOBEC3 mutagenesis in human cancer cells

The APOBEC3 family of cytosine deaminases has been implicated in some of the most prevalent mutational signatures in cancer(1–3). However, a causal link between endogenous APOBEC3 enzymes and mutational signatures in human cancer genomes has not been established, leaving the mechanisms of APOBEC3 mu...

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Detalles Bibliográficos
Autores principales: Petljak, Mia, Dananberg, Alexandra, Chu, Kevan, Bergstrom, Erik N., Striepen, Josefine, von Morgen, Patrick, Chen, Yanyang, Shah, Hina, Sale, Julian E., Alexandrov, Ludmil B., Stratton, Michael R., Maciejowski, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329121/
https://www.ncbi.nlm.nih.gov/pubmed/35859169
http://dx.doi.org/10.1038/s41586-022-04972-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329121/
https://www.ncbi.nlm.nih.gov/pubmed/35859169
http://dx.doi.org/10.1038/s41586-022-04972-y

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