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Mechanisms of APOBEC3 mutagenesis in human cancer cells
The APOBEC3 family of cytosine deaminases has been implicated in some of the most prevalent mutational signatures in cancer(1–3). However, a causal link between endogenous APOBEC3 enzymes and mutational signatures in human cancer genomes has not been established, leaving the mechanisms of APOBEC3 mu...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329121/ https://www.ncbi.nlm.nih.gov/pubmed/35859169 http://dx.doi.org/10.1038/s41586-022-04972-y |