Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures

ABSTRACT: Oncolytic viruses (OVs) represent a novel class of immunotherapeutics under development for the treatment of cancers. OVs that express a cognate or transgenic fusion protein is particularly promising as their enhanced intratumoral spread via syncytia formation can be a potent mechanism for...

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Detalles Bibliográficos
Autores principales: Göbel, Sven, Kortum, Fabian, Chavez, Karim Jaén, Jordan, Ingo, Sandig, Volker, Reichl, Udo, Altomonte, Jennifer, Genzel, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329169/
https://www.ncbi.nlm.nih.gov/pubmed/35767011
http://dx.doi.org/10.1007/s00253-022-12027-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329169/
https://www.ncbi.nlm.nih.gov/pubmed/35767011
http://dx.doi.org/10.1007/s00253-022-12027-5

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