Comprehensive genomic profiling of EWSR1/FUS-CREB translocation-associated tumors uncovers prognostically significant recurrent genetic alterations and methylation-transcriptional correlates

To elucidate the mechanisms underlying the divergent clinicopathologic spectrum of EWSR1/FUS-CREB translocation-associated tumors, we performed a comprehensive genomic analysis of fusion transcript variants, recurrent genetic alterations (mutations, copy number alterations), gene expression, and met...

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Detalles Bibliográficos
Autores principales: Dermawan, Josephine K., Vanoli, Fabio, Herviou, Laurie, Sung, Yun-Shao, Zhang, Lei, Singer, Samuel, Tap, William D., Benayed, Ryma, Bale, Tejus A., Benhamida, Jamal K., Dickson, Brendan C., Antonescu, Cristina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329182/
https://www.ncbi.nlm.nih.gov/pubmed/35347249
http://dx.doi.org/10.1038/s41379-022-01023-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329182/
https://www.ncbi.nlm.nih.gov/pubmed/35347249
http://dx.doi.org/10.1038/s41379-022-01023-9

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