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Enantioselective Hydrocarbamoylation of Alkenes

The asymmetric hydroaminocarbonylation of olefins represents a straightforward approach for the synthesis of enantioenriched amides, but is hampered by the necessity to employ CO gas, often at elevated pressures. We herein describe, as an alternative, an enantioselective hydrocarbamoylation of alken...

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Detalles Bibliográficos
Autores principales: Feng, Sheng, Dong, Yuyang, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329210/
https://www.ncbi.nlm.nih.gov/pubmed/35657208
http://dx.doi.org/10.1002/anie.202206692