Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity

Currently, the humanity is in a fierce battle against various health-related challenges especially those associated with human malignancies. This created the urge to develop potent and selective inhibitors for tumor cells through targeting specific oncogenic proteins possessing crucial roles in canc...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., El Hassab, Mahmoud A., Elsayed, Zainab M., Al-Warhi, Tarfah, Elkady, Hazem, Abo-Ashour, Mahmoud F., Abourehab, Mohammed A. S., Eissa, Ibrahim H., Abdel-Aziz, Hatem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329325/
https://www.ncbi.nlm.nih.gov/pubmed/35896557
http://dx.doi.org/10.1038/s41598-022-15050-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329325/
https://www.ncbi.nlm.nih.gov/pubmed/35896557
http://dx.doi.org/10.1038/s41598-022-15050-8

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