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Assessing agreement between different polygenic risk scores in the UK Biobank

Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratification. However, there are limited investigations on how different PRS diverge from each other in risk prediction of individuals. We compared two recently published PRS for each of three conditions, b...

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Detalles Bibliográficos
Autores principales: Clifton, Lei, Collister, Jennifer A., Liu, Xiaonan, Littlejohns, Thomas J., Hunter, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329440/
https://www.ncbi.nlm.nih.gov/pubmed/35896674
http://dx.doi.org/10.1038/s41598-022-17012-6