Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity

All forms of dementia including Alzheimer’s disease are currently incurable. Mitochondrial dysfunction and calcium alterations are shown to be involved in the mechanism of neurodegeneration in Alzheimer’s disease. Previously we have described the ability of compound Tg-2112x to protect neurons via s...

Descripción completa

Detalles Bibliográficos
Autores principales: Shevtsova, Elena F., Angelova, Plamena R., Stelmashchuk, Olga A., Esteras, Noemi, Vasil’eva, Nataliia A., Maltsev, Andrey V., Shevtsov, Pavel N., Shaposhnikov, Alexander V., Fisenko, Vladimir P., Bachurin, Sergey O., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329451/
https://www.ncbi.nlm.nih.gov/pubmed/35896565
http://dx.doi.org/10.1038/s41598-022-16817-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329451/
https://www.ncbi.nlm.nih.gov/pubmed/35896565
http://dx.doi.org/10.1038/s41598-022-16817-9

Ejemplares similares