[(18)F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

BACKGROUND: Oxidative stress is implicated in the pathogenesis of the most common neurodegenerative diseases, such as Alzheimer’s disease (AD). However, tracking oxidative stress in the brain has proven difficult and impeded its use as a biomarker. Herein, we investigate the utility of a novel posit...

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Detalles Bibliográficos
Autores principales: Hsieh, Chia-Ju, Hou, Catherine, Zhu, Yi, Lee, Ji Youn, Kohli, Neha, Gallagher, Evan, Xu, Kuiying, Lee, Hsiaoju, Li, Shihong, McManus, Meagan J., Mach, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329498/
https://www.ncbi.nlm.nih.gov/pubmed/35895177
http://dx.doi.org/10.1186/s13550-022-00914-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329498/
https://www.ncbi.nlm.nih.gov/pubmed/35895177
http://dx.doi.org/10.1186/s13550-022-00914-x

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