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The Use of AlphaFold for In Silico Exploration of Drug Targets in the Parasite Trypanosoma cruzi

Chagas disease is a devastating neglected disease caused by the parasite Trypanosoma cruzi, which affects millions of people worldwide. The two anti-parasitic drugs available, nifurtimox and benznidazole, have a good efficacy against the acute stage of the infection. But this is short, usually asymp...

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Detalles Bibliográficos
Autores principales: Ros-Lucas, Albert, Martinez-Peinado, Nieves, Bastida, Jaume, Gascón, Joaquim, Alonso-Padilla, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329570/
https://www.ncbi.nlm.nih.gov/pubmed/35909956
http://dx.doi.org/10.3389/fcimb.2022.944748