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The Use of AlphaFold for In Silico Exploration of Drug Targets in the Parasite Trypanosoma cruzi
Chagas disease is a devastating neglected disease caused by the parasite Trypanosoma cruzi, which affects millions of people worldwide. The two anti-parasitic drugs available, nifurtimox and benznidazole, have a good efficacy against the acute stage of the infection. But this is short, usually asymp...
Autores principales: | Ros-Lucas, Albert, Martinez-Peinado, Nieves, Bastida, Jaume, Gascón, Joaquim, Alonso-Padilla, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329570/ https://www.ncbi.nlm.nih.gov/pubmed/35909956 http://dx.doi.org/10.3389/fcimb.2022.944748 |
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