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Generalized Property-Based Encoders and Digital Signal Processing Facilitate Predictive Tasks in Protein Engineering

Computational methods in protein engineering often require encoding amino acid sequences, i.e., converting them into numeric arrays. Physicochemical properties are a typical choice to define encoders, where we replace each amino acid by its value for a given property. However, what property (or grou...

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Detalles Bibliográficos
Autores principales: Medina-Ortiz, David, Contreras, Sebastian, Amado-Hinojosa, Juan, Torres-Almonacid, Jorge, Asenjo, Juan A., Navarrete, Marcelo, Olivera-Nappa, Álvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329607/
https://www.ncbi.nlm.nih.gov/pubmed/35911960
http://dx.doi.org/10.3389/fmolb.2022.898627