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Missing Value Imputation With Low-Rank Matrix Completion in Single-Cell RNA-Seq Data by Considering Cell Heterogeneity

Single-cell RNA-sequencing (scRNA-seq) technologies enable the measurements of gene expressions in individual cells, which is helpful for exploring cancer heterogeneity and precision medicine. However, various technical noises lead to false zero values (missing gene expression values) in scRNA-seq d...

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Detalles Bibliográficos
Autores principales: Huang, Meng, Ye, Xiucai, Li, Hongmin, Sakurai, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329700/
https://www.ncbi.nlm.nih.gov/pubmed/35910201
http://dx.doi.org/10.3389/fgene.2022.952649