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Synthesis and Biological Evaluation of Novel Allobetulon/Allobetulin–Nucleoside Conjugates as AntitumorAgents

Allobetulin is structurally similar tobetulinic acid, inducing the apoptosis of cancer cells with low toxicity. However, both of them exhibited weak antiproliferation against several tumor cell lines. Therefore, the new series of allobetulon/allobetulin–nucleoside conjugates 9a–10i were designed and...

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Detalles Bibliográficos
Autores principales: Wang, Yanli, Huang, Xiaowan, Zhang, Xiao, Wang, Jingchen, Li, Keyan, Liu, Guotao, Lu, Kexin, Zhang, Xiang, Xie, Chengping, Zheng, Teresa, Cheng, Yung-Yi, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329720/
https://www.ncbi.nlm.nih.gov/pubmed/35897914
http://dx.doi.org/10.3390/molecules27154738