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scAPAmod: Profiling Alternative Polyadenylation Modalities in Single Cells from Single-Cell RNA-Seq Data

Alternative polyadenylation (APA) is a key layer of gene expression regulation, and APA choice is finely modulated in cells. Advances in single-cell RNA-seq (scRNA-seq) have provided unprecedented opportunities to study APA in cell populations. However, existing studies that investigated APA in sing...

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Detalles Bibliográficos
Autores principales: Qian, Lingwu, Fu, Hongjuan, Mou, Yunwen, Lin, Weixu, Ye, Lishan, Ji, Guoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329739/
https://www.ncbi.nlm.nih.gov/pubmed/35897701
http://dx.doi.org/10.3390/ijms23158123