Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) incidence, as well as related mortality, has been steadily increasing in the USA and across the globe, partly due to the lack of effective therapeutic options for advanced HCC. Though sorafenib is considered standard-of-care for advanced HCC, it only improves median su...

Descripción completa

Detalles Bibliográficos
Autores principales: Siddharth, Sumit, Kuppusamy, Panjamurthy, Wu, Qitong, Nagalingam, Arumugam, Saxena, Neeraj K., Sharma, Dipali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329836/
https://www.ncbi.nlm.nih.gov/pubmed/35897659
http://dx.doi.org/10.3390/ijms23158083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329836/
https://www.ncbi.nlm.nih.gov/pubmed/35897659
http://dx.doi.org/10.3390/ijms23158083

Ejemplares similares