A Feedback Regulatory Loop Involving dTrbd/dTak1 in Controlling IMD Signaling in Drosophila Melanogaster

Negative regulators of the inflammatory responses are essential for the maintenance of immune homeostasis and organismal fitness. In Drosophila, the deubiquitinase (Dub) dTrbd selectively restricts the K63-linked ubiquitination modification of dTak1, a pivotal kinase of the IMD signaling pathway, to...

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Detalles Bibliográficos
Autores principales: Hua, Yongzhi, Zhu, Yangyang, Hu, Yixuan, Kong, Fanrui, Duan, Renjie, Zhang, Chao, Zhang, Chuchu, Zhang, Shikun, Jin, Yiheng, Ye, Yizhu, Cai, Qingshuang, Ji, Shanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329959/
https://www.ncbi.nlm.nih.gov/pubmed/35911722
http://dx.doi.org/10.3389/fimmu.2022.932268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329959/
https://www.ncbi.nlm.nih.gov/pubmed/35911722
http://dx.doi.org/10.3389/fimmu.2022.932268

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