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Designing Organoid Models to Monitor Cancer Progression, Plasticity and Resistance: The Right Set Up for the Right Question

SIMPLE SUMMARY: In this article, we describe a 3D model that supports the maintenance of cell polarity in cancer and normal cells by growing them on a collagen-coated microsupport. Instead of the spheroids model, the cells are directly positioned to adopt a basal/luminal organization, favoring diffe...

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Detalles Bibliográficos
Autores principales: Doffe, Flora, Bonini, Fabien, Lakis, Emile, Terry, Stéphane, Chouaib, Salem, Savagner, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330027/
https://www.ncbi.nlm.nih.gov/pubmed/35892818
http://dx.doi.org/10.3390/cancers14153559