Harnessing Protein-Ligand Interaction Fingerprints to Predict New Scaffolds of RIPK1 Inhibitors

Necroptosis has emerged as an exciting target in oncological, inflammatory, neurodegenerative, and autoimmune diseases, in addition to acute ischemic injuries. It is known to play a role in innate immune response, as well as in antiviral cellular response. Here we devised a concerted in silico and e...

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Detalles Bibliográficos
Autores principales: Aniceto, Natália, Marques, Vanda, Amaral, Joana D., Serra, Patrícia A., Moreira, Rui, Rodrigues, Cecília M. P., Guedes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330098/
https://www.ncbi.nlm.nih.gov/pubmed/35897894
http://dx.doi.org/10.3390/molecules27154718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330098/
https://www.ncbi.nlm.nih.gov/pubmed/35897894
http://dx.doi.org/10.3390/molecules27154718

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