Cargando…

Newly Synthesized Pyrazolinone Chalcones as Anticancer Agents via Inhibiting the PI3K/Akt/ERK1/2 Signaling Pathway

[Image: see text] A series of novel pyrazolinone chalcones 3–9 have been synthesized through the condensation of azo pyrazolinone derivatives with various aromatic aldehydes. Spectroscopic techniques and elemental analysis have both corroborated this. Furthermore, all compounds were screened in sili...

Descripción completa

Detalles Bibliográficos
Autores principales: Noser, Ahmed A., Shehadi, Ihsan A., Abdelmonsef, Aboubakr H., Salem, Maha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330109/
https://www.ncbi.nlm.nih.gov/pubmed/35910116
http://dx.doi.org/10.1021/acsomega.2c02181