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Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer

Sterol regulatory element binding protein-1 (SREBP-1), a transcription factor with a basic helix–loop–helix leucine zipper, has two isoforms, SREBP-1a and SREBP-1c, derived from the same gene for regulating the genes of lipogenesis, including acetyl-CoA carboxylase, fatty acid synthase, and stearoyl...

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Detalles Bibliográficos
Autores principales: Zhao, Qiushi, Lin, Xingyu, Wang, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330218/
https://www.ncbi.nlm.nih.gov/pubmed/35912181
http://dx.doi.org/10.3389/fonc.2022.952371