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Recurrent Novel P2RY8/IGH Translocations in B-Lymphoblastic Leukemia/Lymphoma

Translocations involving the immunoglobulin heavy chain (IGH) locus are common abnormalities in B-lymphoblastic leukemia/lymphoma (B-ALL) and multiple myeloma. These rearrangements result in a juxtaposition of IGH enhancers to the vicinity of oncogenes, such as MYC and CRLF2, leading to the upregula...

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Detalles Bibliográficos
Autores principales: Fang, Yanglan, Wang, Man, Hu, Shuhong, Wang, Tanzhen, Liu, Yujie, Xiao, Jinyan, Cai, Yiming, Wang, Ying, Qiu, Huiying, Tang, Xiaowen, Chen, Suning, Wu, Depei, Xu, Yang, Liu, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330356/
https://www.ncbi.nlm.nih.gov/pubmed/35912172
http://dx.doi.org/10.3389/fonc.2022.896858