Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention

Background: Splicing factors are essential for nascent pre-mRNA processing and critical in cancer progression, suggesting that proteins with splicing functions represent potential molecular targets for cancer therapy. Here, we investigate the role of splicing factors in glioblastoma multiforme (GBM)...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Han, Mingzhi, Wang, Shuai, Sun, Yanfei, Zhao, Wenbo, Xue, Zhiyi, Liang, Xiangjun, Huang, Bin, Li, Gang, Chen, Anjing, Li, Xingang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330516/
https://www.ncbi.nlm.nih.gov/pubmed/35910786
http://dx.doi.org/10.7150/thno.72248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330516/
https://www.ncbi.nlm.nih.gov/pubmed/35910786
http://dx.doi.org/10.7150/thno.72248

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