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Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention
Background: Splicing factors are essential for nascent pre-mRNA processing and critical in cancer progression, suggesting that proteins with splicing functions represent potential molecular targets for cancer therapy. Here, we investigate the role of splicing factors in glioblastoma multiforme (GBM)...
Autores principales: | Wang, Xu, Han, Mingzhi, Wang, Shuai, Sun, Yanfei, Zhao, Wenbo, Xue, Zhiyi, Liang, Xiangjun, Huang, Bin, Li, Gang, Chen, Anjing, Li, Xingang, Wang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330516/ https://www.ncbi.nlm.nih.gov/pubmed/35910786 http://dx.doi.org/10.7150/thno.72248 |
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