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DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach

Objective: Nobody knows when the COVID-19 pandemic will end or when and where the next coronavirus will outbreak. Therefore, it is still necessary to develop SARS-CoV-2 inhibitors for different variants or even the new coronavirus. Since SARS-CoV-2 uses its surface spike-protein to recognize hACE2,...

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Detalles Bibliográficos
Autores principales: Silwal, Achut Prasad, Thennakoon, Siddhartha Kalpa Samadhi, Arya, Satya Prakash, Postema, Rick Mason, Jahan, Raunak, Phuoc, Chien Minh Tran, Tan, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330529/
https://www.ncbi.nlm.nih.gov/pubmed/35910791
http://dx.doi.org/10.7150/thno.74428