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Inhibition of acylglycerol kinase sensitizes DLBCL to venetoclax via upregulation of FOXO1-mediated BCL-2 expression

Background: Despite of the paradigm change on the treatments of acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) by venetoclax, it has been less successful in the treatment of diffuse large B-cell lymphoma (DLBCL). Here, we explored whether acylglycerol kinase regulates the sensit...

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Detalles Bibliográficos
Autores principales: Ning, Na, Zhang, Si, Wu, Qi, Li, Xun, Kuang, Dong, Duan, Yaqi, Xia, Minghui, Liu, Huicheng, Weng, Junmei, Ba, Hongping, Tang, Zhaohui, Cheng, Xiang, Mei, Heng, Huang, Liu, Ao, Qilin, Wang, Guoping, Hu, Yu, Laurence, Arian, Wang, Jing, Wang, Guihua, Yang, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330532/
https://www.ncbi.nlm.nih.gov/pubmed/35910796
http://dx.doi.org/10.7150/thno.72786