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Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
BACKGROUND: The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of cells. In T cells, the Nck1 isoform promotes T cell receptor signalling as well as actin polymerisation. However, the role of Nck1 in the lipid metabolism in T cells...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330638/ https://www.ncbi.nlm.nih.gov/pubmed/35902806 http://dx.doi.org/10.1186/s12860-022-00436-3 |