Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells

BACKGROUND: The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of cells. In T cells, the Nck1 isoform promotes T cell receptor signalling as well as actin polymerisation. However, the role of Nck1 in the lipid metabolism in T cells...

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Detalles Bibliográficos
Autores principales: Nuiyen, Aussanee, Rattanasri, Araya, Wipa, Piyamaporn, Roytrakul, Sittiruk, Wangteeraprasert, Apirath, Pongcharoen, Sutatip, Ngoenkam, Jutaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330638/
https://www.ncbi.nlm.nih.gov/pubmed/35902806
http://dx.doi.org/10.1186/s12860-022-00436-3

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