All-trans retinoic acid modulates pigmentation, neuroretinal maturation, and corneal transparency in human multiocular organoids

BACKGROUND: All-trans retinoic acid (ATRA) plays an essential role during human eye development, being temporally and spatially adjusted to create gradient concentrations that guide embryonic anterior and posterior axis formation of the eye. Perturbations in ATRA signaling can result in severe ocula...

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Detalles Bibliográficos
Autores principales: Isla-Magrané, Helena, Zufiaurre-Seijo, Maddalen, García-Arumí, José, Duarri, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330659/
https://www.ncbi.nlm.nih.gov/pubmed/35902874
http://dx.doi.org/10.1186/s13287-022-03053-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330659/
https://www.ncbi.nlm.nih.gov/pubmed/35902874
http://dx.doi.org/10.1186/s13287-022-03053-1

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