Human umbilical cord mesenchymal stem cell-derived exosomal miR-335-5p attenuates the inflammation and tubular epithelial–myofibroblast transdifferentiation of renal tubular epithelial cells by reducing ADAM19 protein levels

BACKGROUND: Renal tubular epithelial–myofibroblast transdifferentiation (EMT) plays a key role in the regulation of renal fibrosis. Exosomes derived from human umbilical cord mesenchymal stem cells (hucMSCs) play a crucial role in alleviating renal fibrosis and injury. Additionally, hucMSC-derived e...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Zhenhua, Zhong, Zhihui, Zhang, Yuehan, Tan, Haoling, Deng, Bo, Meng, Guohuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330665/
https://www.ncbi.nlm.nih.gov/pubmed/35902972
http://dx.doi.org/10.1186/s13287-022-03071-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330665/
https://www.ncbi.nlm.nih.gov/pubmed/35902972
http://dx.doi.org/10.1186/s13287-022-03071-z

Ejemplares similares