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Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes

BACKGROUND: Salivary glands produce saliva that play essential roles in digestion and oral health. Derivation of salivary gland organoids from pluripotent stem cells (PSCs) provides a powerful platform to model the organogenesis processes during development. A few studies attempted to differentiate...

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Detalles Bibliográficos
Autores principales: Zhang, Siqi, Sui, Yi, Yan, Shuang, Zhang, Yifei, Ding, Chong, Su, Xiaodong, Xiong, Jingwei, Wei, Shicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330698/
https://www.ncbi.nlm.nih.gov/pubmed/35902913
http://dx.doi.org/10.1186/s13287-022-03033-5