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Structure-Based Bioisosterism Design, Synthesis, Biological Activity and Toxicity of 1,2,4-Oxadiazole Substituted Benzamides Analogues Containing Pyrazole Rings

In order to discover pesticidal lead compounds with high activity and low toxicity, a series of novel benzamides substituted with pyrazole-linked 1,2,4-oxadiazole were designed via bioisosterism. The chemical structures of the target compounds were confirmed via (1)H NMR, (13)C NMR and HRMS analysis...

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Detalles Bibliográficos
Autores principales: Tu, Min-Ting, Shao, Ying-Ying, Yang, Sen, Sun, Bin-Long, Wang, Ying-Ying, Tan, Cheng-Xia, Wang, Xue-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330712/
https://www.ncbi.nlm.nih.gov/pubmed/35897869
http://dx.doi.org/10.3390/molecules27154692