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Structure-Based Bioisosterism Design, Synthesis, Biological Activity and Toxicity of 1,2,4-Oxadiazole Substituted Benzamides Analogues Containing Pyrazole Rings
In order to discover pesticidal lead compounds with high activity and low toxicity, a series of novel benzamides substituted with pyrazole-linked 1,2,4-oxadiazole were designed via bioisosterism. The chemical structures of the target compounds were confirmed via (1)H NMR, (13)C NMR and HRMS analysis...
Autores principales: | Tu, Min-Ting, Shao, Ying-Ying, Yang, Sen, Sun, Bin-Long, Wang, Ying-Ying, Tan, Cheng-Xia, Wang, Xue-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330712/ https://www.ncbi.nlm.nih.gov/pubmed/35897869 http://dx.doi.org/10.3390/molecules27154692 |
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