Impact of Degree of Ionization and PEGylation on the Stability of Nanoparticles of Chitosan Derivatives at Physiological Conditions

Nowadays, the therapeutic efficiency of small interfering RNAs (siRNA) is still limited by the efficiency of gene therapy vectors capable of carrying them inside the target cells. In this study, siRNA nanocarriers based on low molecular weight chitosan grafted with increasing proportions (5 to 55%)...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez Junior, André Miguel, Lima, Aline Margarete Furuyama, Martins, Grazieli Olinda, Tiera, Vera Aparecida de Oliveira, Benderdour, Mohamed, Fernandes, Julio Cesar, Tiera, Marcio José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330794/
https://www.ncbi.nlm.nih.gov/pubmed/35892944
http://dx.doi.org/10.3390/md20080476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330794/
https://www.ncbi.nlm.nih.gov/pubmed/35892944
http://dx.doi.org/10.3390/md20080476

Ejemplares similares