Mitochondrial Oxidative Stress Induces Cardiac Fibrosis in Obese Rats through Modulation of Transthyretin

A proteomic approach was used to characterize potential mediators involved in the improvement in cardiac fibrosis observed with the administration of the mitochondrial antioxidant MitoQ in obese rats. Male Wistar rats were fed a standard diet (3.5% fat; CT) or a high-fat diet (35% fat; HFD) and trea...

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Detalles Bibliográficos
Autores principales: Martínez-Martínez, Ernesto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Nieto, María Luisa, Bravo-San Pedro, José Manuel, Cachofeiro, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330867/
https://www.ncbi.nlm.nih.gov/pubmed/35897655
http://dx.doi.org/10.3390/ijms23158080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330867/
https://www.ncbi.nlm.nih.gov/pubmed/35897655
http://dx.doi.org/10.3390/ijms23158080

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